姓名 汤熙翔
	性别 男
	系别 生物与环境工程系
	学位 博士
	职称 研究员
	职务 中国大洋样品馆（生物）常务副馆长

详细资料

联系方式：13774699879

通讯地址：厦门市思明区大学路184号

邮 编： 361005

Email： tangxixiang@tio.org.cn

主要学术及社会兼职

联合国“国家管辖区外海洋生物多样性养护和可持续利用”国际协定中国代表团海洋遗传资源专题技术专家，中国药学会海洋药物专业委员会委员，中国海洋学会海洋生物资源专业委员会委员，一带一路及葡语国家天然药物创新联盟（澳门）理事。广东医科大学、上海海洋大学、福州大学、福建农林大学、宁波大学、集美大学、汕头大学硕导。

研究领域

海洋生物医药

承担科研课题情况

先后承担国家自然科学基金面上项目、973项目子课题、863项目子课题、科技部国际合作项目子课题、自然资源部重点项目、中国大洋专项子课题、海洋创新示范项目子课题、福建省科技重点项目、厦门市科技项目等30余项。

目前承担了在研的中国大洋环境专项子课题“大洋生物多样性观测与评估（DY-XZ-4，200万RMB）”，自然资源部重点项目“海洋经济高质量发展政策制定实施和监测评估-海洋生物医药产业（680万RMB），外交部中东盟基金重点项目“中国东盟国家蓝色伙伴关系建设-海洋生物医药产业合作（300万RMB）”等国家重点科研任务

出版著作和论文

1. Liu SZ, Xu GX, He FM, Zhang WB, Wu Z, Li MY,Tang X^*, Qiu YK^*. New Sorbicillinoids with Tea Pathogenic Fungus Inhibitory Effect from Marine-Derived FungusHypocrea jecorina H8. Mar Drugs. 2022 Mar 17;20(3):213.

2. Qiu X, Cao X, Jian H, Wu H, Xu G,Tang X^*. Transcriptomic Analysis Reveals that Changes in Gene Expression Contribute toMicrobacterium sediminisYLB-01 Adaptation at Low Temperature Under High Hydrostatic Pressure. Curr Microbiol. 2022 Feb 12;79(4):95.

3. Yu L, Jian H, Gai Y, Yi Z, Feng Y, Qiu X, Shao Z, Tang X^*. Characterization of two novel psychrophilic and piezotolerant strains,Shewanella psychropiezotolerans sp. nov. andShewanella eurypsychro philussp. nov, adapted to an extreme deep-sea environment. Syst Appl Microbiol. 2021 Sep 24;44(6):126266.

4. Qiu X, Yu L, Cao X, Wu H, Xu G, Tang X^*.Halomonas sedimenti sp. nov., a Halotolerant Bacterium Isolated from Deep-Sea Sediment of the Southwest Indian Ocean..Curr Microbiol. 2021 Apr;78(4):1662-1669.

5. Qiu X, Cao X, Xu G, Wu H, Tang X^*.Halomonas maris sp. nov., a moderately halophilic bacterium isolated from sediment in the southwest Indian Ocean.Arch Microbiol. 2021 Aug;203(6):3279-3285.

6. Tang X, Yu L, Yi Y, Wang J, Wang S, Meng C, Liu S, Hao Y, Zhang Y, Cao X, Jian H, Xiao X.Phylogenomic analysis reveals a two-stage process of the evolutionary transition of Shewanella from the upper ocean to the hadal zone.Environ Microbiol. 2021 Feb;23(2):744-756.

7. Yi Z, Cao X, Li H, Jian H, Xu X, Yu L,Tang X^*. Genomic analysis ofMicrobacterium sediminis YLB-01 reveals backgrounds related to its deep-sea environment adaptation. Mar Genomics.2021 Apr;56: 100818.

8. Tang X, Liu SZ, Sun YY, He FM, Xu GX, Fang MJ, Zhen W, Qiu YK.. New Cyclopentenoneacrylic Acid Derivatives from a Marine-Derived FungusTrichoderma atroviride H548. Nat Prod Res. 2020 Mar 11:1-8.

9. Liu SZ^#,Tang X^#, He FM, Jia JX, Hu H, Xie BY, Li MY, Qiu YK. Two new compounds from a mangrove sediment-derived fungusPenicillium polonicumH175. Nat Prod Res. 2020 Nov 4:1-9.

10. Liu SZ, He FM, Bin YL, Li CF, Xie BY,Tang X^*,QiuYK^*. Bioactive compounds derived from the marine-derived fungus MCCC3A00951 and their influenza neuraminidase inhibition activityin vitro andin silico. Nat Prod Res. 2020 Sep 14;1-8.

11. Wang S, Yu L, Tan X, Cao X, Tang X^*,Jian H^*.Genomic analysis ofBrevundimonas mediterranea D151-2-6 isolated from hadal sediment of the Pacific Ocean.Mar Genomics. 2020 Dec;54:100787.

12. Xia JM, Hu XM, Huang CH, Yu LB, Xu RF,Tang X^*, Lin DH^*.Metabolic profiling of cold adaptation of a deep-sea psychrotolerantMicrobacterium sediminis to prolonged low temperature under high hydrostatic pressure. Appl Microbiol Biotechnol. 2020 Jan;104(1): 277-289.

13. Xu X, Yu L, Xu G, Wang Q, Wei S^*, Tang X^*.Bacillus yapensis sp. nov., a novel piezotolerant bacterium isolated from deep-sea sediment of the Yap Trench, Pacific Ocean. Antonie VanLeeuwenhoek.2020 Mar;113(3):389-396.

14. Tang X^*, Yu l, Xu W, Zhang X, Xu X, Wang Q, Wei S , Qiu Y. Fungal diversity of deep-sea sediments in Mid-Oceanic Ridge area of the East Pacific and the South Indian Oceans. Botanica Marina. 2020 doi.org/10.1515/ bot-2018-0112

15. Tang X^*, Yi Z, Xu X, Xu R, Huang P, Yu L.Characterization of cold-tolerant trehalose-6-phosphate synthase from the deep-sea bacterium Microbacterium sediminis YLB-01. Biosci Biotechnol Biochem. 2020 Jan 14:1-9.

16. Tang X, Liu S, Yan X, Tang B, Fang MJ, Wang XM, Wu Z, Qiu YK.Two New Cytotoxic Compounds from a Deep-SeaPenicillum citreonigrum XT20-134. Mar Drugs. 2019 Aug 29;17(9):509.

17. Yu L, Zhou Z, Wei S, Xu X, Wang Q, Xu G, Tang X^*, Yang Q^*.Marinomonas piezotolerans sp. nov., isolated from deep-sea sediment of the Yap Trench, Pacific Ocean.Int J Syst Evol Microbiol. 2019 Mar;69(3): 739-744.

18. Tang X，Yan X, Fu W, Yi L, Tang B, Yu L, Fang M, Wu Z, and Qiu Y. New β-Lactone with Tea Pathogenic Fungus Inhibitory Effect from Marine-derived Fungus MCCC3A00957. J Agric Food Chem. 2019 Mar 13;67(10):2877-2885.

19. Ma X^#, Tang X^#, Lin S, Gong Y, Tran NT, Zheng H, Ma H, Aweya JJ, Zhang Y, Li S.SpBAG1 promotes the WSSV infection by inhibiting apoptosis in mud crab (Scylla paramamosain). Fish Shellfish Immunol. 2019 Nov;94:852-860.

20. Yu L^#, Tang X^#* ,Wei S, Qiu Y, Xu X, Xu G, Wang Q, Yang Q^*.Two novel species of the family Bacillaceae:Oceanobacillus piezotolerans sp. nov. andBacillus piezotolerans sp. nov., from deep-sea sediment samples of Yap Trench. Int J Syst Evol Microbiol. 2019，Oct;69(10): 3022-3030.

21. Yu L^#, Tang X^#*, Wei S, Qiu Y, Xu X, Wang Q, Xu G, Yang Q^*. Isolation and characterization of a novel piezotolerant bacteriumLysinibacillus yapensis sp. nov., from deep-sea sediment of the Yap Trench, Pacific Ocean. Journal of Microbiology. 2019, Jul;57(7): 562-568.

22. Zhang X^#,Tang X^#, Tran NT, Huang Y, Gong Y, Zhang Y, Zheng H, Ma H, Li S.Innate immune responses and metabolic alterations of mud crab (Scylla paramamosain) in response to Vibrio parahaemolyticus infection.Fish Shellfish Immunol. 2019 Jan 9;87:166-177.

23. Li W^#, Tang X^#, Chen Y, Sun W, Liu Y, Gong Y, Wen X, Li S.Characterize a typically Dscam with alternative splicing in mud crabScylla paramamosain.Fish Shellfish Immunol. 2017 Dec;71:305-318.

24. Yan X^#,Tang X^#, Qin D, Yi ZW, Fang MJ, Wu Z, QiuYK.Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library.Mar Drugs. 2016 Jun 1;14(6).

25. Li W^#,Tang X^#, Yan X, Wu Z, Yi ZW, Fang MJ, Su X, Qiu YK.A new macrolactin antibiotic from deep sea-derived bacteriaBacillus subtilis B5.Nat Prod Res. 2016 Apr 13:1-6.

26. Yan X^#,Tang X^#, Chen L, Yi ZW, Fang MJ, Wu Z, Qiu YK.Two new cytotoxic indole alkaloids from a deep-sea sediment derived metagenomic clone.Mar Drugs. 2014 Apr 8;12(4):2156-63.

27. Yu L, Lai Q, Yi Z, Zhang L, Huang Y, Gu L,Tang X^*.Microbacterium sediminissp. nov., a psychrotolerant, thermotolerant, halotolerant, alkalitolerant actinomycete isolated from deep-sea sediment.Int J Syst Evol Microbiol. 2013 Jan;63( 1):25-30.

28. Li N, Yi Z, Wang Y, Zhang Q, Zhong T, Qiu Y, Wu Z, Tang X^*. Differential proteomic analysis of HL60 cells treated with Secalonic Acids F reveals caspase 3–induced cleavage of Rho GDP Dissociation Inhibitor 2. Oncology Reports. 2012,28(6):2016-22.

29. Xu K^#,Tang X^#, Gai Y, Mehmood M A, Xiao X, Wang F .Molecular Characterization of a cold inducible β-galactosidase fromArthrobacter sp. ON14 isolated from Antarctica. J Microbiol Biotech, 2011; 21(3): 236~242.

30. Fu Y^#,Tang X^#,Lai Q, Zhang C, Zhong H, Li W, Liu Y, Chen L, Sun

F,Shao Z.Flavobacterium beibuensesp. nov., isolated from marine sediment.Int J Syst Evol Microbiol. 2011,65（1）：205-209.

31. Chen L^#,Tang X^#, Zheng M, Yi Z, Xiao X, Qiu Y, Wu Z.A novel indole alkaloid from deep-sea sediment metagenomic clone derived Escherichia coli fermentation broth. J Asian Nat Prod Res. 2011, 13（5）：444-448.

近5年专利情况（第一发明人）

1. 具有抗茶叶致病真菌活性的大环内酯化合物及制备与用途。

专利号：ZL 201610268176.4 汤熙翔等；2017年12月15日

2.一株深海来源的酵母菌Q7-7及其应用。

专利号：ZL 201911202650.3 汤熙翔等； 2021年4月20日

3. 一种抗水产致病菌并产脂肪酶的酵母菌Y5及其分离方法和饲料添加剂及其制备方法。

专利号：ZL201911263025.X 汤熙翔等； 2019年12月11日

4.一株产纤维素酶和蛋白酶的酵母菌9-1及微生物制剂制备方法和应用。

专利号：ZL201911262964.2 汤熙翔等； 2019年12月11日

5.一株白僵菌T2-2产生的抗氧化和保湿活性胞外多糖及应用。

专利号：ZL201911297302.9汤熙翔等； 2019年12月17日

获奖情况

获得海洋工程科学技术奖一等奖1项(排名12)

指导硕士生研究方向

海洋生物医药