详细资料

联系方式

通讯地址：泉州师范学院-海洋与食品学院

邮 编：362000

Email：ylchi@qztc.edu.cn

主要学历及工作经历

2002/09-2006/06，河南工业大学，学士

2006/09-2009/07，中国科学院研究生院（中国科学院华南植物园），硕士

2016/09-2019/07，中国科学院大学（中国科学院城市环境研究所），博士

2014/05 -2016/12，中国科学院城市环境研究所，研究实习员

2017/01-2019/08，中国科学院城市环境研究所，助理研究员

2019/09-至今，泉州师范学院，副教授

主要学术及社会兼职

Environmental Science & Technology、Chemosphere、Journal of Environmental Sciences等SCI杂志审稿人

福建省微生物学会人体微生物组与益生菌专业委员会委员

国家自然科学基金委员会函评专家。

研究领域

环境微生物、环境微生态与健康方面的工作、肠道微生物与健康的关系

承担科研课题情况

国家自然科学基金项目，41701576，主持。

中国科学院重点实验室项目，KLUEH-C-201901，主持。

中国科学院重点实验室项目，KLUEH-C-201802，主持。

福建省自然科学基金面上项目，2018J01022，主持。

泉州师范学院引进人才科研项目，H19041，主持。

福建省中青年教师教育科研项目，JAT190525，主持。

国家自然科学基金面上项目，21777158，参加。

国家自然科学基金面上项目，21477124，参加。

国家自然科学基金青年项目，21507128，参加。

福建省中科院STS计划项目，2016T3005，参加。

福建省自然科学基金项目，2017J01028，参加。

福建省自然科学基金引导性项目，2018Y0081，参加。

福建省自然科学基金项目，2018J01020，参加。

出版著作和论文

1. Min, L., Chi, Y*., Dong, S. (2020). Gut microbiota health closely associates with PCB153-derived risk of host diseases. Ecotoxicology and Environmental Safety. 203, 15,111041. (通讯作者)

2. Wang, H., Zhao, P., Huang, Q., Chi, Y*., Dong, S., Fan, J. (2019). Bisphenol-A induces neurodegeneration through disturbance of intracellular calcium homeostasis in human embryonic stem cells-derived cortical neurons. Chemosphere, 229, 618-630. (通讯作者)

3. Chi, Y., Lin, Y., Lu, Y., Huang, Q., Ye, G., & Dong, S. (2019). Gut microbiota dysbiosis correlates with a low-dose PCB126-induced dyslipidemia and non-alcoholic fatty liver disease. Science of the Total Environment, 653, 274-282.

4. Chi, Y., Lin, Y., Zhu, H., Huang, Q., Ye, G., & Dong, S. (2018). PCBs-high-fat diet interactions as mediators of gut microbiota dysbiosis and abdominal fat accumulation in female mice. Environmental Pollution, 239, 332-341.

5. Chi, Y., Wang, H., Lin, Y., Lu, Y., Huang, Q., Ye, G., & Dong, S. (2019). Gut microbiota characterization and lipid metabolism disorder found in PCB77-treated female mice. Toxicology, 420, 11-20.

6. Wang, H., Zhu, Y., Chi, Y*., & Dong, S. (2019). A human embryonic stem cell-based model for benzo[a]pyrene-induced embryotoxicity. Reproductive Toxicology, 85, 26-33. (通讯作者)

7. Chi, Y., Zhang, H., Huang, Q., Lin, Y., Ye, G., Zhu, H., & Dong, S. (2018). Environmental risk assessment of selected organic chemicals based on TOC test and QSAR estimation models. Journal of Environmental Sciences, 64, 23-31.

8. Chi, Y., Huang, Q., Lin, Y., Ye, G., Zhu, H., & Dong, S. (2018). Epithelial-mesenchymal transition effect of fine particulate matter from the Yangtze River Delta region in China on human bronchial epithelial cells. Journal of Environmental Sciences, 66, 155-164.

9. Chi, Y., Wu, Z., Zhong, Y., & Dong, S. (2017). Enantiomeric resolution, stereochemical assignment and toxicity evaluation of TPA enantiomers. Biomedical Chromatography, 31(8), e3924.

10. Chi, Y., Huang, Q., Zhang, H., Chen, Y., & Dong, S. (2016). In situ combined chemical and biological assessment of estrogenic pollution in a water recycling system. Journal of Environmental Sciences, 43, 216-223.

11. Chi, Y. L., Zhang, H. Y., Xue, J. H., Hao, J., Liu, M. F., & Wei, X. Y. (2009). N 2-(1-Methoxycarbonylethyl) guanosine, a new nucleoside coupled with an amino acid derivative from Amanita exitialis. Chinese Chemical Letters, 20 (7), 830-832.

12. Chi, Y. L., Min L. L., Dong, S. J. (2015). Chemical Constituents from Amanita Exitialis. Natural product research and development, 27 (Suppl) 21-23. (In Chinese).

13. Gao, H., Ye, G., Lin, Y., Chi, Y., & Dong, S. (2020). Benzo [a] pyrene at human blood equivalent level induces human lung epithelial cell invasion and migration via aryl hydrocarbon receptor signaling. Journal of Applied Toxicology.

14. Ye, G., Ding, D., Gao, H., Chi, Y., Chen, J., Wu, Z., ... & Dong, S. (2019). Comprehensive metabolic responses of HepG2 cells to fine particulate matter exposure: Insights from an untargeted metabolomics. Science of The Total Environment, 691, 874-884.

15. Ye, G., Chen, G., Gao, H., Lin, Y., Liao, X., Zhang, H., Liu, X., Chi, Y., Huang, Q., Zhu, H., Fan, Y., Dong, S. (2019). Resveratrol inhibits lipid accumulation in the intestine of atherosclerotic mice and macrophages. Journal of Cellular and Molecular Medicine, 1-13.

16. Ye, G., Gao, H., Lin, Y., Ding, D., Liao, X., Zhang, H., Chi, Y., & Dong, S. (2019). Peroxisome proliferator-activated receptor A/G reprogrammes metabolism associated with lipid accumulation in macrophages. Metabolomics, 15(3), 36.

17. Ding, D., Ye, G., Lin, Y., Lu, Y., Zhang, H., Zhang, X., Hong, Z., Huang, Q., Chi, Y.,... & Dong, S. (2019). MicroRNA-26a-CD36 signaling pathway: Pivotal role in lipid accumulation in hepatocytes induced by PM2. 5 liposoluble extracts. Environmental Pollution, 248, 269-278.

18. Ye, G., Gao, H., Wang, Z., Lin, Y., Liao, X., Zhang, H., Chi, Y.,Zhu, H., Dong, S. (2019). PPARα and PPARγ activation attenuates total free fatty acid and triglyceride accumulation in macrophages via the inhibition of Fatp1 expression. Cell Death & Disease, 10(2), 39-39.

19. Huang, Q., Liu, Y., Chen, Y., Fang, C., Chi, Y., Zhu, H., ... & Dong, S. (2018). New insights into the metabolism and toxicity of bisphenol A on marine fish under long-term exposure. Environmental Pollution, 242, 914-921.

20. Huang, Q., Chi, Y., Deng, J., Liu, Y., Lu, Y., Chen, J., & Dong, S. (2017). Fine particulate matter 2.5 exerted its toxicological effect by regulating a new layer, long non-coding RNA. Scientific reports, 7(1), 9392.

21. Huang, Q., Chen, Y., Lin, L., Liu, Y., Chi, Y., Lin, Y., ... & Dong, S. (2017). Different effects of bisphenol A and its halogenated derivatives on the reproduction and development of Oryzias melastigma under environmentally relevant doses. Science of the Total Environment, 595, 752-758.

22. Lu, Y. Y., Lin, Y., Ding, D. X., Su, S., Chi, Q. Q., Zhang, Y. C., ... & Chi, Y. L. (2017). MiR-26a functions as a tumor suppressor in ambient particulate matter-bound metal-triggered lung cancer cell metastasis by targeting LIN28B–IL6–STAT3 axis. Archives of toxicology, 92:1023-1035.

23. Lin, Y., Ding, D., Huang, Q., Liu, Q., Lu, H., Liu, Y., Chi, Y., ... & Wei, J. (2017). Downregulation of miR-192 Causes Hepatic Steatosis and Lipid Accumulation by Inducing SREBF1: Novel Mechanism for Bisphenol A-triggered Non-alcoholic Fatty Liver Disease. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 1862(9), 869-882.

24. Ye, G., Chen, Y., Wang, H. O., Ye, T., Lin, Y., Huang, Q., Chi, Y., ... & Dong, S. (2016). Metabolomics approach reveals metabolic disorders and potential biomarkers associated with the developmental toxicity of tetrabromobisphenol A and tetrachlorobisphenol A. Scientific reports, 6.

25. Lu, Y. Y., Lin, Y., Zhang, H., Ding, D., Sun, X., Huang, Q., ... Chi, Y., & Dong, S. (2016). Evaluation of Volatile Organic Compounds and Carbonyl Compounds Present in the Cabins of Newly Produced, Medium-and Large-Size Coaches in China. International journal of environmental research and public health, 13(6), 596.

26. Huang, Q., Zhang, H., Chen, Y. J., Chi, Y. L., & Dong, S. (2016). The inflammation response to DEHP through PPARγ in endometrial cells. International journal of environmental research and public health, 13(3), 318.

27. Huang, Q., Chen, Y., Chi, Y., Lin, Y., Zhang, H., Fang, C., & Dong, S. (2015). Immunotoxic effects of perfluorooctane sulfonate and di (2-ethylhexyl) phthalate on the marine fish Oryzias melastigma. Fish & shellfish immunology, 44(1), 302-306.

获奖情况

泉州市高层次人才

指导硕士生研究方向

环境（肠道）微生物与健康