
|
姓名王伟毅 |
性别男 |
系别生物与环境工程系 |
学位博士 |
职称副研究员 |
职务无 |
详细资料
联系方式
通讯地址: 厦门市大学路184号
邮 编: 361005
Email: wywang@tio.org.cn
主要学历及工作经历
2018年至今 自然资源部第三海洋研究所 副研究员
主要学术及社会兼职
l Frontiers in Microbiology客座编辑(Guest Associate Editor)
l ACS旗下Journal of Natural Products等期刊长期审稿人
l 中国菌物学会海洋与淡水专委会委员
研究领域
l 天然产物结构解析(运用波谱学及计算化学等技术)
l 天然产物活性筛选及功能评价(抗肿瘤、抗病原微生物等)
承担科研课题情况
在研项目:大洋专项子课题1项(150万),福建省自然科学基金面上项目2项(16万),基本业务费1项(50万)等
出版著作和论文(* = corresponding author, # = contributed equally)
1. Wang, W.#*; Yang, J.#; Liao, Y. Y.; Cheng, G.; Chen, J.; Cheng, X. D.*; Qin, J. J.*; Shao, Z., Cytotoxic Nitrogenated Azaphilones from the Deep-Sea-Derived FungusChaetomium globosum MP4-S01-7.Journal of Natural Products 2020, 83, 1157-1166.
2. Wang, W.#*; Yang, J.#; Liao, Y. Y.; Cheng, G.; Chen, J.; Mo, S.; Yuan, L.; Cheng, X. D.*; Qin, J. J.*; Shao, Z., Aspeterreurone A, a Cytotoxic Dihydrobenzofuran-Phenyl Acrylate Hybrid from the Deep-Sea-Derived FungusAspergillus terreus CC-S06-18.Journal of Natural Products 2020, 83, 1998-2003.
3. Yin, G.-P.; Gong, M.; Xue, G.-M.; Gong, T.; Cao, X.;Wang, W.*; Hu, C.-H.*, Penispidins A-C, Aromatic Sesquiterpenoids fromPenicillium virgatum and Their Inhibitory Effects on Hepatic Lipid Accumulation.Journal of Natural Products2021, 84, 2623-2629.
4. Yu, Z. L.#; Zhou, M. R.#;Wang, W. Y.#; Chang, Y. B.; Sun, C. P.; Lv, X.; Wang, C.; Zhao, W. Y.*; Ma, X. C.*, Cytotoxic diterpenoid dimer containing an intricately caged core fromEuphorbia fischeriana.Bioorganic Chemistry2022,123, 105759.
5. Yu, D.; Qi, S.; Guan, X.; Yu, W.; Yu, X.; Cai, M.; Li, Q.;Wang, W.*; Zhang, W.*; Qin, J. J.*, Inhibition of STAT3 Signaling Pathway by Terphenyllin Suppresses Growth and Metastasis of Gastric Cancer.Frontiers in Pharmacology2022,13, 870367.
6. Feng, S.*;Wang, W.*, Bioactivities and Structure-Activity Relationships of Natural Tetrahydroanthraquinone Compounds: A Review.Frontiers in Pharmacology 2020, 11, 799.
7. Zhang, J.#;Wang, W.#*; Zhou, Y.#; Yang, J.#; Xu, J.; Xu, Z.; Xu, B.; Yan, L.; Cheng, X. D.; Li, M. *; Qin, J. J. *, Terphenyllin Suppresses Orthotopic Pancreatic Tumor Growth and Prevents Metastasis in Mice.Frontiers in Pharmacology 2020, 11, 457.
8. Peng, Y.; Chang, Y.; Sun, C.;Wang, W.; Wang, C.; Tian, Y.; Zhang, B.; Deng, S.; Zhao, W.*; Ma, X.*, Octacyclic and decacyclic ent‑abietane dimers with cytotoxic activity fromEuphorbia fischeriana steud.Chinese Chemical Letters2022, doi: 10.1016/j.cclet.2022.03.003.
9. Zhao, W. Y.; Sun, C. P.; Chang, Y. B.;Wang, W. Y.; Yan, J. K.; Lv, X.; Wang, C.*; Ma, X. C.*, Unprecedented diterpenoid dimers with soluble epoxide hydrolase inhibitory effect fromEuphorbia fischeriana.Organic & Biomolecular Chemistry2022,20, 2508-2517.
10. Hong, X.; Guan, X.; Lai, Q.; Yu, D.; Chen, Z.; Fu, X.; Zhang, B.; Chen, C.; Shao, Z.; Xia, J.*; Qin, J. J.*;Wang, W.*, Characterization of a bioactive meroterpenoid isolated from the marine-derived fungusTalaromyces sp.Applied Microbiology and Biotechnology2022, doi: 10.1007/s00253-022-11914-1.
指导硕士生研究方向
海洋微生物天然产物化学